ABSTRACT
Objective: To determine frequency of Minimal Hepatic Encephalopathy in illiterate patients with compensated cirrhosis
Methods: Illiterate patients with compensated cirrhosis with F4 Score on Shear-wave Elastography were selected for study after informed consent. Sample size was estimated at 106. Selected patients were subjected to two tests for detection of MHE, Number Connection Test A and Block Design Test. Patients taking ? 30 seconds were labelled as Positive for MHE
Result: Out of 110 selected patients 10.9% were alcoholics and in 8.2% of patients no hepatic virus infection was detected. HCV was positive in 48.2% patients while HBV was positive in 13.6% of patients. MHE was detected in 72 [65.5%] of patients. Major differences were found in MHE Stage II and III by two tests. Over all BDT detected more cases and gave higher Staging in Stage II and III as compared to NCT-A test
Conclusion: Minimal Hepatic Encephalopathy [MHE] could be detected in illiterate patients using NCT-A and BDT Tests
ABSTRACT
To determine the frequency of Pott's disease in patients of paraparesis presenting to medical wards of Civil Hospital Karachi. Cross sectional study. This study was conducted in all Medical Wards of Civil Hospital, Karachi, from 1[st] January 2012 to 31 Dec 2012. A total of 133 patients of spastic paraparesis and meeting inclusion criteria were included in this study. Inquiry was carried out regarding age, gender, presenting complaints, duration of illness, past history of TB and site of involvement of spine. Diagnosis of Pott's diasease was made on Magnetic Resonance Imaging [MRI] findings of soft tissue edema, disc space narrowing, paraspinal mass or vertebral collapse. Out of 133 patients, mean age was 47.7 [ +/- 15.6] years with male: Female = 1.6: 1. Out of 133 patients of spastic paraparesis, Pott's disease was diagnosed in 53 [39.8%] cases. Frequency of pott's disease was high in male [M: F = 2.1: 1], 36 [43.9%]. Average age of patients with pott's disease was 49 +/- 13.2 years [Min - Max = 22 - 80 years]. In this study Pott's disease was diagnosed in 39.8% patients of spastic paraparesis. Frequency of pott's disease was high in male gender and older [Age: 31 - 50 years] patients